神经群体动态显示,在电刺激感官附带器时,脊柱回路对自身感受输入的反应被破坏
Natalija Katic Secerovic1, Josep-Maria Balaguer2, Oleg Gorskii3
1School of Electrical Engineering, University of Belgrade, 11000 Belgrade, Serbia; The Mihajlo Pupin Institute, University of Belgrade, 11060 Belgrade, Serbia; Laboratory for Neuroengineering, Institute for Robotics and Intelligent Systems, ETH Zürich, 8092 Zürich, Switzerland.
皮肤神经的电刺激会扰乱脊柱处理四肢位置信号. 这种干扰会影响大脑,表明神经刺激可以改变与之无关的神经功能.
科学领域:
- 神经科学是一个神经科学.
- 计算神经科学是一种神经科学.
- 系统神经科学 系统神经科学
背景情况:
- 神经刺激在感官运动障碍方面取得了进展.
- 电刺激对更广泛的网络动态的影响仍然不清楚.
- 由于相互连接的神经结构,了解非目标效应至关重要.
研究的目的:
- 研究刺激皮肤神经如何影响肢体位置信息的处理.
- 为了确定神经刺激是否会影响干预直接不针对的功能.
主要方法:
- 在子中记录了脊髓内神经活动.
- 通过辐射神经刺激产生的自感输入.
- 应用连续电刺激到辐射神经的皮肤分支.
- 分析神经群体动态以量化刺激效应.
主要成果:
- 同时的皮肤刺激始终破坏了由自感输入产生的神经轨迹.
- 在脊柱处理过程中观察到这种干扰.
- 干扰传播到体感皮层.
结论:
- 皮肤附带器的电刺激会扰乱脊髓处理自身感知信息.
- 神经刺激可以干扰整个神经轴的自然信息处理.
- 研究结果强调需要考虑神经刺激的广泛影响.
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