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Updated: Jul 5, 2025

Implementation of a Real-Time Psychosis Risk Detection and Alerting System Based on Electronic Health Records using CogStack
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通过人口药理动力学建模,对长期作用的阿里皮普拉进行精确医学

Enrique Bandín-Vilar1, Francisco José Toja-Camba1, María Vidal-Millares2

  • 1Pharmacy Department, University Clinical Hospital Santiago de Compostela (CHUS), Spain; Clinical Pharmacology Group, Health Research Institute of Santiago de Compostela (IDIS), Spain; Pharmacology, Pharmacy and Pharmaceutical Technology Department, Faculty of Pharmacy, University of Santiago de Compostela (USC), Spain.

Psychiatry research
|January 21, 2024
PubMed
概括

这项研究开发了一种长效注射性阿里皮普拉 (LAI阿里皮普拉) 和其代谢物的种群药动力学模型. 该模型根据患者的体重,CYP2D6代谢和药物相互作用来个性化剂量,以获得最佳的治疗度.

关键词:
阿里皮普拉 (aripiprazole) 是一种药物.脱水阿里皮普拉 (Dehydroaripiprazole) 是一种消毒剂.长效的注射剂 长效的注射剂基于模型的精确剂量定量.人口的药理动力学.

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