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Updated: Jul 5, 2025

Syntheses, Crystallization, and Spectroscopic Characterization of 3,5-Lutidine N-Oxide Dehydrate
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开发UTX-143是一种选择性-交换亚型5抑制剂,使用阿米洛里德作为化合物

Yusei Shinohara1, Yuki Komiya1, Kashin Morimoto1

  • 1Graduate School of Technology, Industrial and Social Science, Tokushima University, Minamijosanjimacho-2, Tokushima 770-8506, Japan.

Bioorganic & medicinal chemistry
|January 21, 2024
PubMed
概括

研究人员开发了UTX-143,它是Na+/H+交换器5 (NHE5) 的选择性抑制剂,这是结直肠癌中高度表达的蛋白质. 这种化合物通过选择性地杀死癌细胞,显示出作为向抗癌药物的前景.

关键词:
亚米洛化是一种胺.这是一个反入侵防护系统.这是一种抗瘤药物.这是一种NHE5抑制剂.结构与活动的关系.

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