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Updated: Jul 5, 2025

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碳化衍生物产品在动脉瘤大动脉中的积累

Manon Doué1, Guillaume Marques2, Anaïs Okwieka1

  • 1University of Reims Champagne-Ardenne, CNRS, Extracellular Matrix and Cell Dynamics Unit (MEDyC) UMR, Reims, France.

Journal of vascular research
|January 21, 2024
PubMed
概括

蛋白质碳amylation的标记物homocitrulline (HCit) 在人类腹腔大动脉动脉瘤中积累. 然而,这项研究没有证实碳amylation.

关键词:
腹腔大动脉动脉瘤 腹腔大动脉动脉瘤碳amylation 的意思是碳amylation 的意思心血管疾病的心血管疾病.人类素 (Homocitrulline) 是一种类人素.非酶的翻译后修饰.

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Amyloid fibrils are aggregates of misfolded proteins.  Under most circumstances, misfolded proteins are either refolded by chaperone proteins or degraded by the proteasome. However, in the case of a mutation or a disease, these proteins can accumulate to form large clusters and often further assemble to form elongated fibers, called fibrils. 
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