相关实验视频

Updated: Jul 5, 2025

Adoptive Transfer of IL-33-Stimulated Macrophages into Bleomycin-Induced Mouse Models to Study Their Effect on Idiopathic Pulmonary Fibrosis In Vivo
06:29

Adoptive Transfer of IL-33-Stimulated Macrophages into Bleomycin-Induced Mouse Models to Study Their Effect on Idiopathic Pulmonary Fibrosis In Vivo

Published on: May 5, 2023

2.5K

[IL-6通过激活JAK2/STAT3信号通路来增强小鼠膜巨细胞的细胞功能]

Mengqing Hua1, Peiyu Gao2, Fang Fang1

  • 1Department of Immunology, School of Laboratory Medicine, Bengbu Medical College, Anhui Province Key Laboratory of Immunology in Chronic Diseases, Bengbu 233030, China.

Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology
|January 21, 2024
PubMed
概括

介质素-6 (IL-6) 通过通过JAK2/STAT3通路增加actin聚合,从而增强巨细胞细胞分裂. 这一发现提供了对免疫细胞功能和肺损伤潜在治疗点的见解.

更多相关视频

Alveolar Macrophage Phagocytosis and Bacteria Clearance in Mice11:20

Alveolar Macrophage Phagocytosis and Bacteria Clearance in Mice

Published on: March 2, 2019

11.2K
Isolation Protocol of Mouse Monocyte-derived Dendritic Cells and Their Subsequent In Vitro Activation with Tumor Immune Complexes11:48

Isolation Protocol of Mouse Monocyte-derived Dendritic Cells and Their Subsequent In Vitro Activation with Tumor Immune Complexes

Published on: May 31, 2018

11.4K

相关概念视频

The JAK-STAT Signaling Pathway01:20

The JAK-STAT Signaling Pathway

Several cytokine receptors have tightly bound Janus kinase or JAK proteins attached at their cytosolic tail. Small signaling molecules such as cytokines, growth hormones, or prolactins bind to the cytokine receptors and initiate their dimerization. The dimerization brings the cytosolic JAKs together that trans-phosphorylate and activates each other. The activated JAKs now phosphorylate cytosolic tails of the cytokine receptors, which serve as binding sites for adaptor proteins such as  SH2...
8.9K