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G蛋白结合雌激素受体1通过向AMPK依赖的信号传导来改善非酒精性脂肪肝炎

Longlong Li1, Yao Yao1, Yulei Wang1

  • 1Key Laboratory of Animal Physiology and Biochemistry, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, China; MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, China.

The Journal of biological chemistry
|January 21, 2024
PubMed
概括

G蛋白结合雌激素受体1 (GPER1) 激活通过改善胰岛素抵抗和减少肝脏脂肪,有利于非酒精性脂肪肝炎 (NASH). GPER1显示出作为NASH治疗点的前景.

关键词:
通过AMP激活的蛋白激酶激酶被AMP激活.与G蛋白结合的雌激素受体1肝细胞 肝细胞胰岛素耐药性是一种胰岛素耐药性.没有酒精含量的型肝炎.

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