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基于ProtT5和随机森林的粘度预测方法用于治疗mAbs.

Xiaohu Hao1, Long Fan2

  • 1Production and R&D Center I of LSS (Life Science Service), GenScript Biotech Corporation, No. 28, Yongxi Rd., Nanjing, 211110, Jiangsu, China.

European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences
|January 21, 2024
PubMed
概括

在发育早期预测治疗性抗体粘度对于高度配方至关重要. 使用ProtT5和随机森林的一种新的基于序列的方法可以准确预测抗体粘度,有助于药物开发.

关键词:
单克隆抗体是一种单克隆抗体.这就是ProtT5T5.随机森林是随机的森林.粘度 粘度 粘度 粘度 粘度

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