疫苗可预防的疾病:在大量医疗保健学生中发现免疫反应
Paolo Emilio Santoro1, Andrea Paladini2, Ivan Borrelli3
1Department of Life Science and Public Health, Università Cattolica del Sacro Cuore, Rome 00168, Italy; Department of Woman and Child Health and Public Health, Fondazione Policlinico Universitario A. Gemelli IRCCS, Largo Francesco Vito 1, 00168 Rome, Italy.
医疗保健学生对疫苗可以预防的疾病,特别是B型肝炎,造成生物风险的保护不足. 这凸显了医疗学员需要改进疫苗接种策略的必要性.
科学领域:
- 免疫学 免疫学 免疫学
- 职业健康 职业健康 职业健康
- 医学教育 医学教育
背景情况:
- 医疗学生在大学培训期间面临职业危险,包括生物风险.
- 评估疫苗可以预防的关键疾病的血清发病率对于学生的安全至关重要.
研究的目的:
- 在医疗学生中确定抗乙肝 (HBsAg),麻疹,疹,红疹和小的抗体的血清流行率.
- 评估抗体覆盖率,并确定对常见传染病的保护的潜在缺口.
主要方法:
- 在罗马天主教大学从2523名学生 (医学,牙科,卫生专业) 收集的抗体血清学数据.
- 在2013年至2023年期间的初始健康监测访问中收集的数据.
主要成果:
- 血清保护率:乙型肝炎 (44.4%),麻疹 (87.3%),疹 (85.5%),红疹 (94.6%),天花 (95.2%).
- 抗体覆盖的与年龄相关的显著差异 (p < 0.001),除了病.
- 较早的疫苗接种日期与较低的乙型肝炎血清阴性概率相关.
结论:
- 对疫苗可预防疾病的血清阳性率,特别是B型肝炎,在研究的队列中不足.
- 免疫力不足在临床活动期间对学生构成重大生物风险.
- 这些发现强调了强有力的疫苗接种政策和对医疗保健学生的监测的重要性.
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