发现Palbociclib作为一种强大的c-Myc G4稳定剂用于肺癌治疗,使用分子对接,分子动力学模拟和体外活动评估

Jian Gao1, Chao Liang1, Jiacheng Yin2

  • 1School of Medicine, Anhui University of Science and Technology, Huainan, China.

Molecular diversity
|January 21, 2024
PubMed
概括

作为CDK4/6抑制剂的Palbociclib通过稳定c-Myc G4结构,有效抑制肺癌细胞的生长. 这种新的治疗方法在治疗由异常c-Myc活动驱动的癌症方面表现有前途.

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