银和氧化铁纳米颗粒的绿色合成介导了光热对Blastocystis hominis的影响
Shaimaa M I Alexeree1, Hanan M Abou-Seri2, Hala E Shams El-Din2
1Department of Laser Application in Metrology, Photochemistry, and Agricultural, National Institute of Laser Enhanced Science, Cairo University, Giza, Egypt. sh.alexeree@niles.edu.eg.
Lasers in medical science
|January 21, 2024
概括
银和氧化铁纳米颗粒,当被LED光激活时,通过光热疗法有效地杀死细胞胞体人类. 这种方法提供了一种有前途的新策略,用于对抗耐药寄生虫感染.
科学领域:
- 纳米技术纳米技术
- 寄生虫学的寄生虫学
- 生物医学工程 生物医学工程
背景情况:
- 寄生虫对抗寄生虫药物的耐药性需要新的治疗策略.
- 纳米颗粒显示出作为寄生虫疾病的药物载体的希望.
- 使用纳米颗粒的光热疗法提供了一种新的治疗方式.
研究的目的:
- 评估银纳米颗粒 (Ag NPs) 和氧化铁纳米颗粒 (Fe3O4 NPs) 作为抗寄生虫剂对抗Blastocystis hominis.
- 为了研究这些纳米粒子在LED光线激活时的光热效应.
- 评估光热激活纳米颗粒在降低B. hominis囊活性的有效性.
主要方法:
- 使用UV-Vis光谱,泽塔电位和TEM合成和描述AgNP和Fe3O4NP.
- 在体外测试纳米粒子在黑暗条件下对B. hominis的疗效.
- 使用LED光 (400-700nm) 诱导光热效应,并使用共聚焦显微镜和图像分割算法评估B. hominis囊的活力.
主要成果:
- 鉴定证实了合成纳米粒子的特性.
- 通过LED灯光对AgNP和Fe3O4NP的光热激活导致了高热.
- 使用光热活性纳米粒子观察到B. hominis囊数量的显著减少.
结论:
- 光热活性纳米颗粒显示出作为对抗Blastocystis hominis.有效剂的显著潜力.
- 这种光热方法为开发新的抗寄生虫疗法提供了一种新的策略.
- 这项研究强调了一种有希望的方法来克服寄生虫感染中耐药性的方法.
相关概念视频
Green Algae
Green algae, also referred to as chlorophytes, are different from red algae in having the chloroplasts containing chlorophylls a and b, which give them their distinct green hue. However, they lack phycobiliproteins, preventing them from developing the red or blue-green pigmentation seen in red algae. In terms of photosynthetic pigment composition, green algae closely resemble plants and share a close evolutionary relationship with them. Taxonomically Green algae belong to Phylum Chlorophyta in...
Microbes and Other Elemental Cycles
Microbial activity plays a pivotal role in the biogeochemical cycling of iron and manganese, especially at the redox gradients characteristic of stratified aquatic environments. These cycles are driven by microbial transformations between oxidized and reduced forms of the metals, allowing organisms to exploit them for metabolic energy and structural purposes.Iron Cycling Across Redox GradientsIn neutral, oxygen-rich surface waters, iron is predominantly found in its oxidized, insoluble ferric...
Microbial Leaching
Microbial leaching, also known as bioleaching, is an environmentally favorable method for extracting metals from low-grade ores using specific microorganisms. This biotechnological approach is particularly valuable for mining operations targeting copper, gold, and uranium, where traditional extraction methods may be economically or environmentally impractical.Copper Leaching and Microbial CatalysisIn copper bioleaching, crushed ore is arranged into heaps and irrigated with a dilute sulfuric...


