相关实验视频
Updated: Jul 5, 2025

09:17
Point-of-Care Lung Ultrasound in Adults: Image Acquisition
Published on: March 3, 2023
6.0K
卧卧姿势后肺水密度和体积的动态变化
Thomas Goodhart1, Peter Seres1, Justin Grenier1
1Department of Biomedical Engineering, University of Alberta, Edmonton, Alberta, Canada.
Magnetic resonance in medicine
|January 22, 2024
概括
躺卧后,肺体积减少,肺水密度显著增加. 这些肺水和体积的生理变化应在成像分析过程中考虑.
科学领域:
- 肺部生理学 肺部生理学
- 医疗成像医学成像
- 量化MRI是指数量化的MRI.
背景情况:
- 身体的位置对肺部生理有很大影响.
- 了解肺部的液体转移对于准确的成像解释至关重要.
研究的目的:
- 为了量化肺部相对水密度 (rLWD),肺体积和肺部总水密度随着时间的推移而发生的变化.
- 为了确定这些参数的时间动态.
主要方法:
- 使用高效的超短TE脉冲序列与球k空间轨迹用于水密度加权肺成像.
- 在定位后25分钟内,在9名健康志愿者身上获得了功能残余容量的3D图像.
- 测量全球和区域rLWD,肺体积和肺总水量,通过洗研究进行验证.
主要成果:
- 全球相对肺水密度 (rLWD) 显著增加 (p=0.001) 从31.8%增加到34.8%.
- 肺体积显著下降 (p<0.001),从2390毫升降至2130毫升.
- 在rLWD中观察到一个显著的胸部到背部梯度,胸部增加1.8%,背部增加5.4%.
结论:
- 在几十分钟的时间里,仰卧的位置会导致肺体积显著减少,肺水密度增加.
- 在此期间,肺部总水量略有减少.
- 准确评估 rLWD 需要考虑自卧卧位置以来的时间,以避免偏差.
更多相关视频
相关概念视频
Pressure Relationships in Thoracic Cavity
2.3K
Breathing, otherwise known as pulmonary ventilation, is the process of air movement into and out of the lungs. The main mechanisms propelling pulmonary ventilation are atmospheric pressure (Patm), intra-pulmonary (Ppul ) or intra-alveolar pressure (Palv) within the alveoli, and intrapleural pressure (Pip) within the pleural cavity.
Breathing Mechanisms
Both intra-alveolar and intrapleural pressures rely on specific lung properties. The ability to breathe—allowing air to enter the lungs...
Breathing Mechanisms
Both intra-alveolar and intrapleural pressures rely on specific lung properties. The ability to breathe—allowing air to enter the lungs...
2.3K
Factors Affecting Pulmonary Ventilation
1.4K
Besides the pressure difference between the external environment and the lungs, the airflow rate and ease of pulmonary ventilation are also influenced by three other factors: surface tension of the fluid in the alveoli, compliance of the lungs, and airway resistance.
Alveolar Surface Tension
The alveolar fluid lines the luminal surface of the alveoli and exerts a force called surface tension. This force is caused by the polar water molecules in the liquid being more strongly attracted to each...
Alveolar Surface Tension
The alveolar fluid lines the luminal surface of the alveoli and exerts a force called surface tension. This force is caused by the polar water molecules in the liquid being more strongly attracted to each...
1.4K
Pulmonary Ventilation: Inhalation
3.7K
Pulmonary ventilation is a vital process that ensures the exchange of oxygen and carbon dioxide in the lungs. It refers to the movement of air into and out of the lungs, enabling the body to obtain oxygen and remove waste carbon dioxide. In this article, we will explore the intricacies of pulmonary ventilation, including its underlying principles, mechanisms, and the interplay of pressures within the respiratory system.
Boyle's law becomes particularly pertinent when examining respiratory...
Boyle's law becomes particularly pertinent when examining respiratory...
3.7K
Breathing
59.3K
The process of breathing, inhaling and exhaling, involves the coordinated movement of the chest wall, the lungs, and the muscles that move them. Two muscle groups with important roles in breathing are the diaphragm, located directly below the lungs, and the intercostal muscles, which lie between the ribs. When the diaphragm contracts, it moves downward, increasing the volume of the thoracic cavity and creating more room for the lungs to expand. When the intercostal muscles contract, the ribs...
59.3K
Respiratory Volumes
1.5K
Respiratory volumes are crucial metrics, meticulously measured to quantify the air exchanged in and out of the lungs during various phases of the breathing cycle. These precise measurements are vital for assessing lung function, diagnosing respiratory conditions, and monitoring overall respiratory health. Each parameter provides specific insights into the mechanics of breathing and the functional capacity of the lungs.
Tidal Volume (TV) Tidal volume (TV) is the air inhaled or exhaled in a...
Tidal Volume (TV) Tidal volume (TV) is the air inhaled or exhaled in a...
1.5K
Pulmonary Cycle: Exhalation
1.6K
In terms of human respiration, the act of expelling air, known as exhalation (or expiration), operates on the principle of pressure gradients. During expiration, the pressure within the lungs exceeds that of the surrounding atmosphere. Under normal conditions, quiet breathing involves passive exhalation and is free of muscular contractions. This is because the exhalation process is driven by the natural elastic recoil of the lungs and chest wall, both of which have an inherent tendency to...
1.6K

