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Updated: Jul 5, 2025

Implementing Patch Clamp and Live Fluorescence Microscopy to Monitor Functional Properties of Freshly Isolated PKD Epithelium
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cGAS激活加速了自体主导多囊性病的进展

Miran Yoo1, Jonathan C Haydak, Evren U Azeloglu

  • 1Division of Nephrology, Icahn School of Medicine at Mount Sinai, New York, New York.

Journal of the American Society of Nephrology : JASN
|January 22, 2024
PubMed
概括

自体主导多囊性病 (ADPKD) 涉及免疫细胞. 阻断循环氨酸单酸-氨酸单酸合成酶 (cGAS) /干扰素基因刺激器 (STING) 途径可以减少囊的生长,并保持ADPKD中的功能.

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