性结肠炎中常见的萨尔科佩尼亚与疾病活动相关
Pardhu B Neelam1, Rimesh Pal2, Pankaj Gupta3
1Department of Gastroenterology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Intestinal research
|January 22, 2024
概括
肌肉质量和力量的损失 - - 萨尔科佩尼亚 - - 在患有活性的性结肠炎 (UC) 的患者中更为普遍. 这种情况与UC患者的疾病严重程度增加有关.
科学领域:
- 胃肠病学 胃肠病学
- 老年病的医生 老年病的医生
- 肌肉骨健康 肌肉骨健康
背景情况:
- 性结肠炎 (UC) 是一种慢性炎症性肠病.
- 萨尔科佩尼亚和UC疾病严重程度之间的关联尚未得到充分确立.
- 萨科佩尼亚会影响肌肉质量,力量和身体功能.
研究的目的:
- 使用修订后的定义来确定UC患者中肉类的患病率.
- 为了研究沙尔科佩尼亚和UC疾病严重程度之间的关系.
- 为了评估sarcopenia与UC的临床结果的关联.
主要方法:
- 在114名UC患者的横截面研究中.
- 根据肌肉质量 (DXA),手握强度和4米步行测试评估的萨尔科佩尼亚.
- 根据梅奥得分分级的疾病活动;由肌肉质量和力量减少来定义的肉类.
主要成果:
- 麻症的发病率为21.9%,严重的麻症为12.2%.
- 在患有活跃或严重UC (P<0.001) 的患者中,肉症的发生率显著增加 (P<0.001).
- 在多变量分析中,更高的梅奥得分和更低的BMI与肉症有关.
结论:
- 性肠炎和严重的性肠炎与性肠炎的疾病活性有显著的相关性.
- 研究结果强调了在UC管理中评估肌肉健康的重要性.
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