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怀孕期莱姆病妇女的产科和新生儿结局

Julien M Courville¹, Nicholas Czuzoj-Shulman², Andrea R Spence²

¹Department of Obstetrics and Gynecology, Jewish General Hospital, McGill University, Montreal, Quebec, Canada.

International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics

|January 22, 2024

概括

孕期莱姆病 (LD) 增加了怀孕患者胎盘断裂和早产的风险. 虽然并发症存在,但大多数带有LD的怀孕可以在标准的医疗保健环境中进行管理.

科学领域:

产科和妇科产科和妇科
传染性疾病传染性疾病
公共卫生公共卫生

背景情况:

莱姆病 (LD) 发病率在全球范围内有所增加.
孕期LD与不良妊娠结果有关,但证据是相互矛盾的.
了解LD对怀孕的影响对于母亲和婴儿健康至关重要.

研究的目的:

调查妊娠LD与产科和新生儿结局之间的关联.
提供有关怀孕期间与LD相关的风险的最新证据.

主要方法:

使用美国医疗保健成本和利用计划的国家 (全国) 住院患者样本 (2016-2019) 的回顾性队列研究.
包括妊娠期LD (ICD-10代码A692x) 的孕妇患者和没有LD的对照组.
使用描述性统计和调整的多变量逻辑回归模型进行分析.

主要成果:

该研究分析了2,943,575名孕妇入院,其中226人被诊断患有LD.
孕期LD与胎盘断裂 (aOR,3.45) 和早产 (aOR,1.58) 的风险显著增加.
妊娠期LD患者更有可能是白人,年长,拥有私人保险,收入更高.

结论:

妊娠期LD是胎盘断裂和早产的重要危险因素.
尽管增加了风险,但LD复杂的怀孕通常可以在常规医疗保健环境中进行管理.
进一步的研究可能会探索孕期LD的特定管理策略.

关键词:

莱姆病是莱姆病的一种疾病.怀孕期间的莱姆病.新生儿的结果.的产科结果.怀孕怀孕怀孕怀孕怀孕怀孕并发症怀孕并发症

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