与德尔塔-8THC零售可用性相关的因素在德克萨斯州沃思堡,2021-2022年
C R LoParco1,2, A Y Kong3,4, R A Yockey1
1School of Public Health, University of North Texas Health Science Center, Fort Worth, TX, USA.
Substance use & misuse
|January 22, 2024
概括
在德克萨斯州沃思堡,尽管存在法律不确定性,但Delta-8 THC的零售供应仍然保持一致. 烟草和大麻零售商更有可能储存Delta-8 THC,在酒精零售商附近注意到社会经济差异.
科学领域:
- 大麻研究 大麻研究
- 公共卫生 公共卫生
- 社会经济分析 社会经济分析
背景情况:
- 德尔塔-8 THC是一种受欢迎的,不受联邦监管的精神活性大麻产品.
- 关于Delta-8 THC产品的零售可用性的数据有限.
- 了解它的分布对于公共卫生和监管工作至关重要.
研究的目的:
- 为了评估德克萨斯州沃思堡的Delta-8 THC的零售供应情况.
- 检查影响可用性的因素,包括零售许可证类型和区域剥夺.
- 评估在德克萨斯州法律挑战之前和之后的可用性变化.
主要方法:
- 在福特沃思进行了电话调查,调查了酒精,烟草或大麻许可证的零售地点.
- 在德克萨斯州诉讼新闻之前和之后,在两个时间点评估了Delta-8 THC的可用性.
- 利用后勤回归来分析许可证类型,区域剥夺指数 (ADI) 分数和Delta-8 THC可用性之间的关联.
主要成果:
- 在第一时间,Delta-8 THC的零售可用性为11%,在第二时间为9%.
- 烟草和可消费大麻许可证与更高的Delta-8 THC可用性密切相关.
- 酒精许可证和高ADI分数的地点显示,在第二时间出售Delta-8 THC的几率增加.
结论:
- 在德克萨斯州沃思堡,Delta-8 THC的零售业务保持稳定,无论法律含糊性如何.
- 在Delta-8 THC可用性的社会经济差异与酒精零售地点有关.
- 未来的法规应考虑接近敏感地点,特别是处于不利地位的地区,并加强零售商对许可证的遵守.
相关概念视频
Chemotherapy-Induced Nausea and Vomiting: Cannabinoids
279
Tetrahydrocannabinol (THC) is a phytocannabinoid that primarily interacts with the CB1 receptor, a type of G protein-coupled receptor (GPCR) predominantly in and around the chemoreceptor trigger zone (CTZ) and emetic center. THC also blocks the serotonin receptor activity in the dorsal vagal complex (DVC) by inhibiting serotonin release. THC exerts its anti-emetic effects through these interactions, which are beneficial for patients undergoing chemotherapy.
Two synthetic agonists of THC,...
Two synthetic agonists of THC,...
279
Factors Affecting Drug Distribution: Miscellaneous Factors
340
Drug distribution in the human body is a complex process influenced by various individual factors, including age, pregnancy, obesity, diet, body water composition, pH levels, and specific disease conditions.
Age plays a significant role due to differences in body composition among different age groups. Infants, for instance, have a higher proportion of total body water and lower albumin levels, a protein that binds drugs in the bloodstream. This unique composition in infants enhances the...
Age plays a significant role due to differences in body composition among different age groups. Infants, for instance, have a higher proportion of total body water and lower albumin levels, a protein that binds drugs in the bloodstream. This unique composition in infants enhances the...
340
Hallucinogens and Psychedelics
166
Hallucinogens are psychoactive substances that profoundly alter perceptual experiences, generating unreal visual and sensory images. Often referred to as psychedelic drugs — a term derived from the Greek words "psyche" (mind) and "delos" (revealing) — these substances include marijuana and lysergic acid diethylamide (LSD), among others. These drugs vary in intensity and effects.
Marijuana, derived from the dried leaves and flowers of the hemp plant, contains...
Marijuana, derived from the dried leaves and flowers of the hemp plant, contains...
166
Factors Influencing Drug Absorption: Drug Dissolution
508
The pharmacokinetic journey of drugs from solid oral dosage forms into systemic circulation is multifaceted. It begins with disintegration, a prerequisite ensuring a solid dosage form's subdivision into minute particles. Dissolution occurs next as these granulated entities solubilize in gastrointestinal fluids. This solubilization is crucial for the succeeding stage, permeation, which describes the traversal of the drug across the intestinal membrane and its subsequent entry into the blood...
508
Factors Affecting Drug Response: Overview
2.0K
When it comes to infants and young children, they are typically administered smaller doses of medication in comparison to adults. This is primarily because their organ functions still need to fully develop, meaning their bodies are not as efficient at metabolizing or eliminating drugs. Additionally, their blood-brain barrier is more permeable than in adults. As a result, high concentrations of drugs can easily penetrate the central nervous system (CNS), potentially leading to neurological...
2.0K
Factors Influencing Drug Absorption: Physicochemical Parameters
278
The physicochemical characteristics of drugs play a crucial role in formulating stable and bioavailable drug products. The solubility of a drug, governed by the varying pH along the GI tract and its dissociation constant (pKa), is pivotal in determining its ionization state and absorption rate. Notably, weak acids and bases remain unionized and are absorbed more rapidly.
Enhanced drug absorption can be achieved by reducing particle sizes and increasing surface areas, thereby facilitating...
Enhanced drug absorption can be achieved by reducing particle sizes and increasing surface areas, thereby facilitating...
278


