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Updated: Jul 5, 2025

Optimized LC-MS/MS Method for the High-throughput Analysis of Clinical Samples of Ivacaftor, Its Major Metabolites, and Lumacaftor in Biological Fluids of Cystic Fibrosis Patients
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Optimized LC-MS/MS Method for the High-throughput Analysis of Clinical Samples of Ivacaftor, Its Major Metabolites, and Lumacaftor in Biological Fluids of Cystic Fibrosis Patients

Published on: October 15, 2017

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开发venetoclax与2-hydroxypropyl-beta-cyclodextrin包容复合物的开发,以提高生物可用性

Smalant Kishor Patil1, Padakanti Sandeep Chary1, Sarvan Maddipatla2

  • 1Pharmaceutical Nanotechnology Research Laboratory, Department of Pharmaceutics, National Institute of Pharmaceutical Education and Research (NIPER), Hyderabad, Telangana, India.

Journal of biomolecular structure & dynamics
|January 22, 2024
PubMed
概括

这项研究开发了venetoclax的循环德克斯特林复合物,显著提高了其溶解性和抗癌功效. 这种新型配方改善了口服生物可用性,并对肺癌细胞表现出强烈的活性.

关键词:
循环德克斯特林 (Cyclodextrin) 是一种循环德克斯特林.在MTT测试中使用MTT测试.在每一个阶段.肺上皮质 肺上皮质分子建模分子建模

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