炎症性肠道疾病中的眼科表现:要注意它
Giulia Migliorisi1,2, Giovanna Vella3, Arianna Dal Buono1
1IBD Center, IRCCS Humanitas Research Hospital, Via Manzoni 56, Rozzano, 20089 Milan, Italy.
Cells
|January 22, 2024
概括
眼部肠外表现 (O-EIMs) 影响约10%的炎症性肠病 (IBD) 患者,特别是那些患有克罗恩病 (CD) 患者. 及时诊断和多学科管理对于这些与IBD相关的眼睛疾病至关重要.
科学领域:
- 眼科医生 眼科 眼科
- 胃肠病学 胃肠病学
- 免疫学 免疫学 免疫学
背景情况:
- 炎症性肠道疾病 (IBD) 是一种慢性胃肠道疾病,具有多种肠外表现 (EIM).
- 眼部EIMs (O-EIMs) 影响大约10%的IBD患者,在克罗恩病 (CD) 中更频繁.
- 在O-EIM中出现的症状包括眼睛发红,光恐惧症,疼痛和视力模糊,影响生活质量.
研究的目的:
- 审查IBD患者O-EIM的流行,发病和基于证据的管理.
- 突出协作,多学科方法的必要性,以便及时诊断和治疗.
- 总结目前用于IBD眼部表现的治疗策略.
主要方法:
- 在PubMed上进行了全面的文献搜索,截至2023年12月.
- 确定了专注于IBD中O-EIMs的发病,流行病学和治疗的研究.
- 综合了相关的研究,以提供该领域的概述.
主要成果:
- O-EIMs的发病包括免疫失调,共享的抗原,遗传因素和系统性炎症 (例如,互白蛋白,细胞因子).
- 管理策略范围从局部/全身类固醇到免疫调节剂和生物疗法,如抗TNF-alpha.
- 多学科的方法对于有效的O-EIM管理至关重要.
结论:
- O-EIM是IBD的一个严重并发症,需要专门的注意.
- 了解复杂的病原体是定制治疗的关键.
- 胃肠科医生和眼科医生之间的协作护理对于最佳的患者结果至关重要.
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