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基于AGE的增殖性糖尿病视网膜病变模型中的神经血管关系

Juan S Peña1, Ranjini K Ramanujam1, Rebecca A Risman1

  • 1Department of Biomedical Engineering, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, USA.

Bioengineering (Basel, Switzerland)
|January 22, 2024
PubMed
概括

先进的糖化终产品 (AGEs) 在糖尿病中损害内血液视网膜屏障 (iBRB),增加炎症和血块形成,导致视力丧失.

关键词:
愤怒的愤怒 愤怒的愤怒先进的糖化最终产品.糖尿病视网膜病变 糖尿病视网膜病变内部血液视网膜屏障 内部血液视网膜屏障血管疾病是血管疾病.

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DefinitionDiabetic retinopathy is a microvascular complication of diabetes affecting the retinal blood vessels.Risk FactorsDiabetic retinopathy is present in almost all individuals with type 1 diabetes and more than 60% of those with type 2 diabetes after two decades of disease.The risk increases with poor glycemic control, hypertension, dyslipidemia, smoking, pregnancy, and puberty.Although cataracts and glaucoma are also more frequent in people with diabetes, retinopathy remains the leading...