预测器和风险因素的分析 后多斑瘤综合征的预测器和风险因素
Stefano Fusco1, Michelle E Bauer1, Ulrike Schempf1
1Department of Internal Medicine I, Section of Gastroenterology, Gastrointestinal Oncology, Hepatology, Infectiology and Geriatrics, University Hospital of Tübingen, 72076 Tübingen, Germany.
Diagnostics (Basel, Switzerland)
|January 22, 2024
概括
后多角瘤综合征 (PPS) 的危险因素包括有状多形态,部位置和缺少内皮质瘤. 升高的CRP和温度预测了通过多角切除术进行结肠镜检查后PPS的发展.
科学领域:
- 胃肠病学 胃肠病学
- 内镜手术 进行内镜手术
- 临床风险评估临床风险评估
背景情况:
- 术后多角切除综合征 (PPS) 是经过结肠镜多角切除术后的一种已知的并发症.
- 现有的文献对PPS提出了各种定义和标准,需要标准化识别.
- 了解PPS预测因子对于患者管理和程序安全至关重要.
研究的目的:
- 为了确定独立的风险因素和预测器,开发后多叶瘤综合征 (PPS).
- 建立PPS的明确诊断标准.
- 评估多特征和患者因素对PPS发病率的影响.
主要方法:
- 一个回顾性单心研究,包括966名接受结肠镜检查的患者 (2015年10月 - 2020年6月).
- 主要定义PPS为干预后超过6小时的腹痛.
- 分析患者数据以确定多特征,临床标志物和PPS发展之间的相关性.
主要成果:
- 9.7%的患者患有PPS (腹部疼痛>6小时).
- 确定了独立的危险因素:有状多形态,多腺瘤,部位置,以及缺少内皮质瘤.
- 加高的C反应蛋白 (CRP) 与发烧 (>37.5°C) 相结合,成为PPS的积极预测因素.
结论:
- 证实了PPS的四个关键风险因素:状聚形态,状聚位置,缺少内皮质瘤和多腺瘤配置.
- CRP水平和温度升高是PPS的重要预测因素.
- 预计越来越多地采用冷陷多角切除术将减少PPS发病率.
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