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相关概念视频

Gastritis-II: Pathophysiology01:17

Gastritis-II: Pathophysiology

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Gastritis is marked by disruption of the mucosal barrier that usually protects the stomach tissue from digestive juices and manifests in acute and chronic forms.
In acute gastritis, the gastric mucosa becomes swollen and red and undergoes superficial erosion. Superficial ulceration may lead to bleeding.
In chronic gastritis, persistent or repeated insults lead to chronic inflammatory changes and, eventually, thinning or atrophy of the gastric tissue.
Gastritis can stem from various causes, each...
330
Chronic Pancreatitis I: Introduction01:24

Chronic Pancreatitis I: Introduction

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The pancreas, an elongated and flat gland situated behind the stomach, serves a vital function in digesting food and managing blood sugar levels.
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
89
Gastritis-I: Introduction and Types01:27

Gastritis-I: Introduction and Types

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Gastritis, defined by the inflammation or irritation of the stomach lining or gastric mucosa, manifests in several distinct forms: acute, chronic, reactive, and a specific subtype known as autoimmune metaplastic atrophic gastritis.
Acute gastritis presents as a sudden inflammation triggered by various stressors to the stomach lining, such as exposure to corrosive agents, local irritants like aspirin and other NSAIDs, alcohol consumption, radiation therapy, physical trauma, severe burns, sepsis,...
439
Autoimmune Disorders01:29

Autoimmune Disorders

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Autoimmune diseases are a group of disorders in which the body's immune system mistakenly attacks its own cells, tissues, and organs. This results from an overactive immune response against substances and tissues normally present in the body. Let's delve into the concept and mechanism of autoimmune diseases from an immune system point of view, explore different causes and examples of such diseases, and discuss potential solutions.
Concept and Mechanism of Autoimmune Diseases
The immune...
442
Liver Regeneration01:24

Liver Regeneration

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The liver is an important organ in vertebrates that plays an essential role in metabolism. It is also responsible for storing and redistributing nutrients such as carbohydrates, fats, and vitamins in the body. Additionally, the liver releases bile salts which are critical for digesting food and eliminating toxic metabolites from the body.
Cells of Liver
The liver comprises four major types of cells— hepatocytes, stellate, Kupffer, and sinusoidal endothelial cells. The hepatocytes are...
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The CYP2D6 Animal Model: How to Induce Autoimmune Hepatitis in Mice
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自免疫性肝炎:从进化到现状 - - 一位病理学家的观点

Puja Sakhuja1, Surbhi Goyal1

  • 1Department of Pathology, Govind Ballabh Pant Institute of Postgraduate Medical Education and Research, New Delhi 110002, India.

Diagnostics (Basel, Switzerland)
|January 22, 2024
PubMed
概括

自身免疫性肝炎 (AIH) 是一种免疫媒介性肝病. 诊断依赖于整合临床,生物化学,血清学和肝脏活检的发现,不断变化的标准强调组织学.

科学领域:

  • 肝病学 肝病学是一种肝病学.
  • 免疫学 免疫学 免疫学
  • 胃肠病学 胃肠病学

背景情况:

  • 自身免疫性肝炎 (AIH) 是一种由免疫系统功能障碍引起的慢性肝病.
  • 如果不治疗,它可能会发展为肝硬化,并且经常被误诊.
  • AIH主要影响年轻女性,但可以发生在所有年龄组.

研究的目的:

  • 审查AIH不断变化的诊断标准.
  • 突出目前诊断方法的局限性和实用性.
  • 强调肝脏组织学在AIH诊断和管理中的关键作用.

主要方法:

  • 对AIH现有文献和诊断指南的审查.
  • 对诊断和组织学标准的修改进行分析.
  • 强调整合临床,生化,血清学和组织学数据.

主要成果:

  • 没有单一的生物标志物或组织学特征是AIH的病理特征.
  • 自1993年以来,诊断标准不断发展,最近对组织学标准达成共识.
  • 肝脏活检对于诊断,分期和排除其他疾病至关重要.

结论:

关键词:
国际自身免疫性肝炎小组自体免疫性肝炎的发生.组织学 组织学额叶性肝炎 额叶性肝炎血细胞集群的血细胞集群门性肝炎是门性肝炎.简化诊断标准 简化诊断标准

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  • 准确的AIH诊断需要一个综合的方法,整合多个参数.
  • 不断发展的诊断标准,特别是组织学建议,改善了AIH评估.
  • 肝脏组织学仍然是诊断和管理自身免疫性肝炎的基石.