功能性头作为空间认知功能障碍
Hayo A Breinbauer1,2, Camilo Arévalo-Romero1, Karen Villarroel1
1Laboratory for Clinical Neuro-Otology and Balance-Neuroscience, Department of Neuroscience, Facultad de Medicina, Universidad de Chile, Santiago 8331150, Chile.
Brain sciences
|January 22, 2024
概括
持续的姿势感知性头 (PPPD) 显著影响空间导航和认知功能. 这表明,被破坏的空间认知可能是PPPD病理生理学的关键因素.
科学领域:
- 神经科学是一个神经科学.
- 认知心理学 认知心理学
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
背景情况:
- 持续的姿势感知性头 (PPPD) 是一种常见的慢性头状况,原因不明.
- 空间认知障碍被假设为PPPD的核心特征.
- 了解PPPD的病理生理学对于有效治疗至关重要.
研究的目的:
- 研究空间认知在持久性姿势感知性头 (PPPD) 中的作用.
- 为了比较PPPD患者的认知和前庭功能与健康对照组和其他前庭障碍患者.
- 为了确定潜在的病理生理机制背后的PPPPD.
主要方法:
- 对19名PPPD患者进行了心理认知测试,包括用于空间导航的虚拟莫里斯水迷宫.
- 参与者还接受了焦虑,抑郁,记忆,注意力,计划和执行功能的评估.
- 对照组包括12名健康对照组和20名患有其他前体疾病的患者;前体功能和脑MRI也被评估.
主要成果:
- PPPD患者在非中心空间导航和视觉空间认知任务 (伦敦塔楼,步道制作B) 中表现出显著的缺陷.
- 因子分析确定空间导航和先进的视觉空间功能是PPPD的核心,与症状严重程度相关.
- 通过MRI没有发现混性病理,并使用前庭功能测试进行比较.
结论:
- 持续的姿势感知性头 (PPPD) 似乎广泛影响更高的认知功能,特别是空间认知.
- 形成详细的认知空间地图的中断被认为是PPPD的潜在原因.
- 这些发现强调了认知评估在PPPD诊断和管理中的重要性.
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