相关实验视频

Updated: Jul 5, 2025

Probing the Brain in Autism Using fMRI and Diffusion Tensor Imaging

Probing the Brain in Autism Using fMRI and Diffusion Tensor Imaging

Published on: September 12, 2011

磁共振图像质量对结构和功能大脑连接的影响:马斯特里赫特研究

Joost J A de Jong^1,2, Jacobus F A Jansen^1,2, Laura W M Vergoossen^1,2

¹Department of Radiology and Nuclear Medicine, Maastricht University Medical Centre, 6202 AZ Maastricht, The Netherlands.

|January 22, 2024

概括

图像质量在大人口研究中显著影响大脑连接度. 图像质量差,特别是头部运动和低信号噪声比,可能会混与年龄,性别和BMI相关的结果.

科学领域:

神经成像是一种神经成像.
人口神经科学人口神经科学
生物医学工程生物医学工程

背景情况:

磁共振成像 (MRI) 对于对大脑结构和功能的基于人群的研究至关重要.
先进的MRI技术,如扩散权重MRI (dMRI) 和静止状态fMRI (rs-fMRI) 绘制大脑连接的地图.
数据采集和处理偏差可能会扭曲连接性指标及其人口/临床关联.

研究的目的:

调查图像质量指标对大脑连接的影响.
评估信号与噪声比,头部运动和地图表模板不匹配如何影响dMRI和rs-fMRI衍生连接.
确定图像质量对大脑连接和人口/临床因素之间的关联的影响.

主要方法:

分析了马斯特里赫特研究中的5110名参与者的dMRI和rs-fMRI数据.
图像质量指标的量化,包括信号噪声比和头部运动.
统计建模以评估图像质量指标和大脑连接度量之间的关系.

主要成果:

增加头部运动显著降低了结构性大脑连接 (R2高达0.169,p < 0.001).
降低的信号噪声比对功能性大脑连接有负面影响 (R2高达0.013,p < 0.001).
图像质量指标大大改变了大脑连接和年龄 (高达-59%),性别 (高达-25%) 和BMI (高达+14%) 之间的关联.

结论:

图像质量是大脑连接的基于人口的神经成像研究中的关键混因素.
头部运动和信号噪声比是影响结构和功能连接的关键因素.
对图像质量的考虑对于大队伍中大脑连接发现的准确解释至关重要.

关键词:

大脑的连接性大脑的连接性图像质量图像质量的质量磁共振成像技术的使用神经成像是一种神经成像.人口-队列研究.

更多相关视频

Co-analysis of Brain Structure and Function using fMRI and Diffusion-weighted Imaging

Co-analysis of Brain Structure and Function using fMRI and Diffusion-weighted Imaging

Published on: November 8, 2012

High-resolution Functional Magnetic Resonance Imaging Methods for Human Midbrain

High-resolution Functional Magnetic Resonance Imaging Methods for Human Midbrain

Published on: May 10, 2012

相关概念视频

Magnetic Resonance Imaging

Magnetic Resonance Imaging

Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...

Brain Imaging

Brain Imaging

Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans), magnetic resonance imaging (MRI), functional magnetic resonance imaging (fMRI), and Transcranial Magnetic...