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味觉功能的定量评估及其与人口统计学及其系统性发病率的关联
Doron J Aframian1,2,3, Alaa Zedan2, Weaam Agbariah2
1Sjögren's Syndrome Center, Hadassah Medical Center, Jerusalem 9112001, Israel.
味觉功能障碍或味觉障碍与老年和男性性别有关. 它也与严重的创伤,化疗,缺乏,口腔炎综合征和毒素暴露有关.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 化学感应研究 化学感应研究
- 老年医学 老年医学
背景情况:
- 味觉功能障碍是影响生活质量的常见投诉.
- 了解与味觉功能障碍相关的因素对于诊断和管理至关重要.
- 需要定量评估方法来客观地衡量味觉障碍.
研究的目的:
- 通过验证的味道条测量口味功能障碍与人口因素之间的关联进行分析.
- 调查味觉功能障碍与各种并发症之间的关系.
- 为了确定具有更高风险的味觉障碍的特定患者群体.
主要方法:
- 来自Orofacial Chemosensory Center (2017-2020) 的患者记录的回顾性分析.
- 包括272名受试者 (50.4%为女性,平均年龄为53.5岁).
- 使用经过验证的味道带进行口味功能的定量评估 (总口味得分范围为0-16).
主要成果:
- 年龄较大与总口味评分有显著的负相关性 (p=0.001).
- 男性的总体,味和苦味的评分明显较差 (p<0.001).
- 严重的创伤,化疗,缺乏,口腔炎综合征 (BMS) 和有毒化学物质暴露与各种口味障碍有关.
结论:
- 胃口功能障碍与老年,男性性别和特定的并发症有显著的关联.
- 定量品味评估对于诊断患有主观味道投诉的患者来说很重要.
- 对于表现出味觉障碍的患者,建议进行系统性评估.
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