新兴中风风险因素:关注传染病和环境决定因素
Sajid Hameed1, Nurose Karim2, Mohammad Wasay3
1Department of Neurology, University of Virginia, Charlottesville, VA 22903, USA.
Journal of cardiovascular development and disease
|January 22, 2024
概括
新兴的中风风险因素,如空气污染,肠道微生物群的变化,高海拔和感染是可以修改的. 针对这些因素的干预措施可以显著减少全球中风发病率和死亡率.
科学领域:
- 神经学 神经学
- 环境健康 环境健康
- 微生物学 微生物学
背景情况:
- 在全球范围内,中风仍然是导致死亡和残疾的主要原因.
- 传统的风险因素已经确立,但新出现的因素需要调查.
- 了解新的风险因素对于全面的中风预防策略至关重要.
研究的目的:
- 审查新出现的中风风险因素.
- 突出环境和生物因素对中风风险的影响.
- 强调这些新出现的风险因素的可修改性.
主要方法:
- 关于新出现的中风风险因素研究的文献综述.
- 对将空气污染,肠道微生物群,高海拔和系统性感染与中风联系起来的数据进行分析.
- 综合这些因素的机制和影响的证据.
主要成果:
- 空气污染,特别是细颗粒物,与中风风险和死亡率的增加有关,特别是在发展中国家.
- 肠道微生物群的改变可能会通过炎症和动脉样硬化促进中风的发展.
- 高海拔 (3000米以上) 和全身感染 (病毒和细菌) 与血栓形成和缺血性中风的风险增加有关.
结论:
- 新出现的风险因素包括空气污染,肠道微生物群失生症,高海拔地区和系统性感染,这些都对中风发病率有很大影响.
- 这些因素是可修改的,为有针对性的干预提供了机会.
- 解决这些新型风险因素可能会导致全球中风负担大幅减少.
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