新出现的呼吸道病毒的动物病和动物人类病
Ahmed Magdy Khalil1,2, Luis Martinez-Sobrido1, Ahmed Mostafa1,3
1Disease Intervention & Prevention and Host Pathogen Interactions Programs, Texas Biomedical Research Institute, San Antonio, TX, United States.
Frontiers in cellular and infection microbiology
|January 22, 2024
概括
流感和SARS-CoV-2等流行性病毒可以在人类和动物之间跳跃 (动物病和逆动物病). 监测这些病毒传播对于理解病毒演变和开发有效干预措施至关重要.
科学领域:
- 病毒学 病毒学
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 人类大流行主要是由A型流感病毒 (IAV) 和SARS-CoV-2引起的.
- 这些病毒起源于自然水库,并通过中间宿主适应,促进动物传播.
- 动物病和逆动物病 (动物人类病) 涉及这些病毒在人类和动物之间传播.
研究的目的:
- 在H1N1和SARS-CoV-2大流行期间审查动物病和逆动物病事件.
- 突出跨物种病毒传播对病毒进化的影响.
- 讨论对抗流行病毒的预防和治疗策略.
主要方法:
- 关于病毒性动物病和流行病的科学文献的综述.
- 对A型流感病毒和SARS-CoV-2病毒传播动态的分析.
- 在物种间传播的背景下,对病毒演变的研究.
主要成果:
- 甲型流感病毒和SARS-CoV-2已经显示出显著的动物感染和逆动物感染潜力.
- 跨物种传播有助于病毒适应,进化和对干预措施的潜在耐药性.
- 了解这些事件是预测和管理未来流行病威胁的关键.
结论:
- 持续监测病毒性 zoonosis 和反向 zoonosis 是非常重要的.
- 一个健康和一个世界的方法是必要的,以减轻与大流行病毒演变和治疗耐药性相关的风险.
- 积极的监测和干预策略对于全球卫生安全至关重要.
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