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与多次DKA入院在一个大型县医院相关的社会和代谢特征
Josh Peedikayil1, Shrenika Reddy2, Rohit Nair1
1UT Southwestern Medical School, Dallas, TX 75390, USA.
吸食物质,特别是大麻和烟草,与1型糖尿病 (T1DM) 患者的糖尿病酸性脂肪酸 (DKA) 复发性入院有关. 针对物质使用的干预措施可能会减少这个人群中DKA的发作.
科学领域:
- 内分泌学 在内分泌学.
- 公共卫生 公共卫生
- 成 药物 药物 药物 药物
背景情况:
- 糖尿病酸症 (DKA) 是1型糖尿病 (T1DM) 的严重并发症.
- 经常性DKA入院对医疗保健系统和患者造成重大负担.
- 健康的社会决定因素可能会影响DKA的复发.
研究的目的:
- 为了确定区分T1DM患者的社会因素,单个与多个DKA入院.
- 在城市,安全网医院环境中探索物质使用和DKA复发之间的关联.
主要方法:
- 对DKA (2019-2021) 住院的T1DM患者电子健康记录的回顾性分析.
- 收集和统计分析实验室值,人口统计和社会历史.
- 使用后勤回归来确定多次DKA入院的预测因素.
主要成果:
- 在单个和多个DKA入院组之间,在实验室值,停留时间或社会经济因素方面没有发现显著差异.
- 患有多次DKA入院的患者表现出更高的物质使用障碍率 (60.9%对33.0%),特别是大麻,烟草和精神活性物质.
- 药物使用,包括任何药物使用 (OR 3.17) 和大麻使用 (OR 3.70),显著增加了多次DKA入院的风险.
结论:
- 药物使用是T1DM患者的潜在预测因素,有复发DKA的风险.
- 识别使用物质的患者可能允许针对性的干预措施来减少DKA的复发.
- 这些发现与管理T1DM患者的类似社区医院人群有关.
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