转录基因剖析揭示了GDF6介导的人类脂肪衍生干细胞与细胞核的基因差异化过程中的关键早期反应基因

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Updated: Jun 15, 2026

Generation of Human Adipose Stem Cells through Dedifferentiation of Mature Adipocytes in Ceiling Cultures
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Generation of Human Adipose Stem Cells through Dedifferentiation of Mature Adipocytes in Ceiling Cultures

Published on: March 7, 2015

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Hamish T J Gilbert1, Francis E J Wignall1, Leo Zeef2

  • 1Division of Cell Matrix Biology and Regenerative Medicine, School of Biological Sciences, Faculty of Biology, Medicine and Health University of Manchester, Manchester Academic Health Sciences Centre Manchester UK.

JOR spine
|January 22, 2024
PubMed
概括

增长分化因子6 (GDF6) 驱动脂肪衍生干细胞 (ASC) 分化成核 (NP) 样细胞. 这项研究揭示了早期的基因反应和信号通路,这些通路对于开发有效的细胞疗法来治疗椎间盘退化至关重要.

关键词:
脂肪衍生干细胞来源的干细胞.不同化的差异化差异化.椎间盘之间的椎间盘.它的核是脉冲的脉冲.再生医学是一种再生医学.翻译学 翻译学 翻译学

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