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Updated: Jul 27, 2026

Endobronchial Ultrasound-guided Intratumoral Injection of Cisplatin for the Treatment of Isolated Mediastinal Recurrence of Lung Cancer
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基于的辅助化疗对表皮生长因子受体突变肺腺癌的疗效

Ken Onodera1, Isao Yokota2, Yuki Matsumura3

  • 1Department of Thoracic Surgery, Institute of Development, Aging and Cancer, Tohoku University, Sendai, Miyagi, Japan.

Journal of thoracic disease
|January 22, 2024
PubMed
概括

基于的辅助化疗可能对EGFR突变肺腺癌患者没有好处. 这项研究发现,与单独手术相比,这些患者的整体生存率没有显著改善.

关键词:
肺癌是一种肺癌.辅助性化疗是一种辅助性化疗.表皮生长因子受体突变 (EGFR突变)基于的化学疗法.

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Genetic polymorphisms in drug targets have emerged as critical determinants of interindividual variability in drug response and toxicity. Pharmacogenomic investigations increasingly focus on identifying these variations to personalize and optimize therapeutic interventions. A drug target may be a receptor, enzyme, or signaling protein involved in pharmacologic responses or disease-related pathways. While early pharmacogenetic studies focused primarily on drug metabolism, current research...