为抗微生物药物管理制定产科专用指标和干预措施
Jeffrey Man Hay Wong1, Denise J Wooding2, Sarah E Leung3
1Department of Obstetrics and Gynecology, University of British Columbia, Vancouver, British Columbia, Canada.
产科中的抗菌药物管理是独一无二的. 这项研究建立了基线指标,并发现抗微生物原始化和审计/反干预措施是可行的,以改善处方模式.
科学领域:
- 产科和妇科 产科和妇科
- 传染性疾病 传染性疾病
- 药房和治疗药物 药房和治疗药物
背景情况:
- 与一般住院患者相比,在产科中使用抗微生物药物存在独特的挑战.
- 建立基准抗菌药物管理 (AMS) 指标对于制定有针对性的干预措施至关重要.
- 这项研究侧重于一家三级医疗中心内的住院产科患者群体.
研究的目的:
- 在住院产科患者群体中描述基线抗菌药物管理 (AMS) 指标.
- 在这个独特的患者群体中应用特定的AMS干预措施.
- 为未来产科的AMS编程奠定基础.
主要方法:
- 来自药房数据库的抗微生物消费数据的回顾性审查.
- 每月在两个预先确定的日期进行点流行调查 (PPS),以评估抗菌素使用情况.
- 对非协议化抗菌素处方进行前性审计和每日提供反.
主要成果:
- 抗微生物药物治疗的平均持续时间 (LOT) 为每100个患者日12天,主要贡献者是红红,阿莫西西林和安比西林.
- 点患病率调查显示,28.8%的产科住院患者接受了抗菌药物,11.2%被认为是不合适的.
- 协议化抗微生物药物显示不适当性减少了62% (p=0.027),并执行了90%的审计/反建议.
结论:
- 产科中的抗菌素处方模式需要特别注意和量身定制的AMS策略.
- 抗微生物原始化显著减少了在产科住院患者的不适当使用.
- 预期审计和反是提高产科AMS的有效和可行的干预措施.
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