儿童的复发性呼吸道感染可能与维生素A状况有关:一项病例对照研究
Xuguang Zhang1, Xuezheng Dai2, Xianan Li2
1Department of Child Healthcare, The Sixth Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China.
Frontiers in pediatrics
|January 22, 2024
概括
儿童维生素A水平较低与复发性呼吸道感染 (RRTIs) 有关. 确保足够的维生素A摄入量和状态对于预防儿科患者的RRTIs至关重要.
科学领域:
- 儿童营养学 儿童营养学
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 复发性呼吸道感染 (RRTIs) 是儿童的重大健康问题.
- 新兴研究表明,维生素A缺乏与RRTIs的发展之间存在潜在联系.
研究的目的:
- 调查维生素A状况与儿童的RRTIs之间的关联.
- 检查饮食维生素A摄入量与RRTIs发生率之间的关系.
主要方法:
- 一项涉及2592名0.5-14岁儿童的调查在中国黑龙江省.
- 分类为RRTI组 (1,039名儿童) 和对照组 (1,553名健康儿童).
- 用HPLC测量血清维生素A水平;使用食物频率问卷 (FFQ) 评估饮食摄入量.
主要成果:
- 与对照组相比,接受RRTIs的儿童的血清维生素A度明显较低 (0.27 ± 0.09 mg/L对比0.29 ± 0.09 mg/L,P < 0.01).
- 维生素A不足和缺乏与RRTIs的几率增加有关 (OR分别为1.32和1.95).
- 低摄入维生素A丰富的食物,如动物肝脏,与较低的RRTI发病率有关.
结论:
- 血清维生素A度低与中国东北部儿童RRTIs发病率较高有关.
- 低维生素A水平和当前的呼吸道感染症状都与RRTI的发展相关.
- 摄入不够的富含维生素A的食物是导致RRTIs的一个因素.
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