指数预测慢性心力衰竭患者的死亡率:一项前性观察性研究
Bryan Richard Sasmita1, Yuhe Zhao1,2, Ming Gong1
1Department of Cardiology, the First Affiliated Hospital of Chongqing Medical University, 400016, Chongqing, China.
Global heart
|January 22, 2024
概括
在慢性心力衰竭患者中,较高的指数 (EI) 预测了长期死亡率的增加. 这种液体状况标志物可以识别具有所有原因和心血管死亡风险较大的个体.
科学领域:
- 心脏病学 心脏病学
- 临床医学 临床医学
- 生物医学工程 生物医学工程
背景情况:
- 慢性液体积累是心力衰竭的一个关键机制,导致呼吸障碍和等症状.
- 湿疹指数 (EI) 作为患者细胞外体积和拥堵状态的可靠指标.
研究的目的:
- 在被诊断为患有慢性心力衰竭 (CHF) 的患者中调查水指数 (EI) 的预后意义.
主要方法:
- 预计将有401名连续CHF患者的招生 (2019年8月至2021年10月).
- 使用InBody S10.0测量水指数 (EI).
- 主要终点:长期所有原因和心血管死亡率.
主要成果:
- 患有高EI (>0.397) 的患者年龄较大,心房动,N端大脑尿素和肌素的发病率较高.
- 在中位数为1200天的随访期间,高EI组显示所有原因 (43.8%vs30.3%) 和心血管死亡率 (17.5%vs13.0%) 显着更高.
- 多变量分析证实EI> 0.397作为所有原因 (HR 1.959) 和心血管死亡率 (HR 2.051) 的独立预测因素.
结论:
- 入院指数 (EI) 有效地预测慢性心力衰竭患者的长期死亡率.
- 升高的EI与所有原因和心血管死亡率的风险增加有关.
- 以EI为指导的管理可能为CHF患者提供一个有前途的治疗方法.
更多相关视频
10:21Evaluation of Hydration Status by Bioelectrical Impedance Vector Analysis in Patients with Ischemic Heart Disease Undergoing Exercise Stress Test
Published on: September 22, 2023
650
07:59Bedside Ultrasound for Guiding Fluid Removal in Patients with Pulmonary Edema: The Reverse-FALLS Protocol
Published on: July 28, 2018
11.2K
相关概念视频
01:22Heart Failure Drugs: Diuretics
384
Heart failure and kidney perfusion are interconnected in a complex way. Reduced renal perfusion and venous congestion are two significant factors that contribute to renal dysfunction in heart failure. The kidneys, primarily responsible for fluid balance in the body, are adversely affected due to compromised cardiac output and increased venous pressure. In response to reduced renal perfusion, the kidneys activate neurohumoral mechanisms to restore balance. However, these mechanisms can be...
384
01:17Pathophysiology of Heart Failure
1.6K
Heart failure (HF) is a progressive syndrome involving ventricles that leads to inadequate cardiac output. It can be classified based on location and output or ejection fraction. Ejection fraction (EF) is an essential measurement in the diagnosis and surveillance of HF. Reduced EF corresponds to systolic heart failure (HFrEF). However, HF with preserved ejection fraction (HFpEF) is becoming increasingly prevalent. Also known as diastolic HF, this form of HF is related to aging. The...
1.6K
01:26Heart Failure Drugs: Inhibitors of Renin-Angiotensin System
432
The activation of the sympathetic nervous system and the renin-angiotensin-aldosterone system (RAAS) contributes to cardiac remodeling, and inhibiting the RAAS is a pharmacological target in heart failure management. As a result, neurohumoral modulation is a crucial treatment principle for managing heart failure. This approach involves using medications like ACE inhibitors (ACEIs), angiotensin receptor blockers (ARBs), β-blockers, mineralocorticoid receptor antagonists (MRAs), and neutral...
432
01:26Imbalances in Cardiac Output
1.4K
The heart's primary function is to pump blood throughout the body, maintaining a balance between blood sent out (cardiac output) and blood returning (venous return). If this balance is disrupted, it can result in congestive heart failure (CHF), a severe condition where the heart becomes an inefficient pump, leading to inadequate blood circulation.
CHF can occur due to the failure of either side of the heart. Left-side failure leads to pulmonary congestion—the right side continues to send...
CHF can occur due to the failure of either side of the heart. Left-side failure leads to pulmonary congestion—the right side continues to send...
1.4K