对比度增强超声波的定性和定量参数的诊断值,用于区分分化甲状腺癌与良性结节的区分
Jinfang Fan1, Lingling Tao1, Weiwei Zhan2
1Department of Ultrasound, RuiJin Hospital, LuWan Branch, School of Medicine, Shanghai Jiaotong University, Shanghai, China.
Frontiers in endocrinology
|January 22, 2024
概括
用对比增强超声波 (CEUS) 有效地区分甲状腺癌与良性结节使用特定参数. 关键指标包括异质增强,低增强,不清楚的边际和峰值强度,有助于临床决策.
科学领域:
- 放射学 放射学是一门学科.
- 在瘤学瘤学.
- 医疗成像医学成像
背景情况:
- 甲状腺结节很常见,区分良性和恶性类型对于适当的管理至关重要.
- 准确的手术前诊断可以防止不必要的手术,并指导治疗策略.
研究的目的:
- 评估对比增强超声波 (CEUS) 的定性和定量参数在区分分化甲状腺癌与良性甲状腺结节的诊断性能.
- 确定可以帮助甲状腺结节的差异诊断的关键CEUS特征.
主要方法:
- 一项涉及290个病理确认的甲状腺结节的研究.
- 对临床特征和CEUS参数 (增强模式,边缘,峰值强度,度等) 的分析. 使用单变量和多变量逻辑回归.
- 在良性和恶性结节之间对CEUS发现的比较.
主要成果:
- 多变量分析揭示了良性和恶性结节在年龄,结节大小,异质增强,低增强,不清楚的边缘,内部峰值强度和外部度方面存在显著差异.
- 诸如性别,环增强,洗进/洗出模式,达到峰值的时间 (TP) 和曲线下的面积 (AUC) 等参数没有显著差异.
- 诸如异质增强,低增强,不清楚的边缘和内部峰值强度等CEUS参数是恶性瘤的强有力的指标.
结论:
- 与对比度增强的超声波 (CEUS) 在差异化甲状腺癌和良性结节的差异诊断中具有显著价值.
- 特定的CEUS定性和定量参数可以为有关甲状腺结节的临床治疗决策提供可靠的基础.
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