免疫性血小板缺血症儿童免疫接种的安全性
Xiangshi Wang1, Tianxing Feng2, Chuning Wang1
1Department of Infectious Disease, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai 201102, China.
在中国,免疫性血栓塞缩症 (ITP) 的儿童接种疫苗覆盖率较低. 在ITP缓解后的再免疫通常是安全的,大多数儿童完成了补充疫苗,尽管有些人经历了复发.
科学领域:
- 儿科 儿科 儿科
- 免疫学 免疫学 免疫学
- 公共卫生 公共卫生
背景情况:
- 免疫性血小板缺血 (ITP) 对儿童免疫提供了独特的挑战.
- 在中国,ITP儿童的照顾者中,对疫苗的犹是普遍存在的.
- 评估这一群体的免疫状态和安全性至关重要.
研究的目的:
- 评估中国ITP儿童免疫状况.
- 分析免疫接种和血小板缺血之间的关系.
- 为了确定ITP缓解后再免疫的安全性.
主要方法:
- 对186名有ITP病史的儿童进行了回顾性研究.
- 再接种疫苗后的两年随访建议.
- 对疫苗覆盖率,与疫苗相关的血小板缺血和ITP复发率的分析.
主要成果:
- 总体而言,年龄相应的疫苗接种率为57.9%.
- 与疫苗相关的血小板缺血发生在53.2%的儿童中.
- 80.6%的儿童完成了补充免疫接种;4名患者在重新免疫接种后复发.
结论:
- 在患有ITP的儿童中,重新免疫接种通常是安全的,通常不会导致复发.
- 在接种各种类型的疫苗后,不仅仅是含有麻疹的疫苗,可以发生ITP.
- 诸如慢性血小板缺血和先前与疫苗相关的事件等因素影响不完全的追赶免疫.
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