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Updated: Jul 5, 2025

Human Liver Microphysiological System for Assessing Drug-Induced Liver Toxicity In Vitro
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2,4-D除草剂诱导的肝毒性:揭示受损的肝功能和相关生物标志物

Rafael Xavier Martins1,2, Matheus Carvalho2, Maria Eduarda Maia1,2

  • 1Post-Graduation Program in Biochemistry, Department of Biochemistry and Molecular Biology, Building 907, Campus Pici, Federal University of Ceará, Fortaleza 60455-970, Brazil.

Toxics
|January 22, 2024
PubMed
概括

2,4-二基酸 (2,4-D) 除草剂的暴露会通过降低抗氧化能力和增加氧化应激而导致肝损伤. 需要进一步的研究才能充分理解它的作用机制.

关键词:
农业化学品农业化学品新出现的污染物污染物.氧化应激是一种氧化应激.水的污染 污染水的污染

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相关概念视频

Toxic Reactions: Overview01:26

Toxic Reactions: Overview

When toxic substances penetrate the human body, they disseminate to various tissues, undergoing metabolic changes. This process yields reactive metabolites that may covalently bind with specific target molecules, resulting in toxicity.
Toxicity falls into two primary categories: local and systemic.
Local toxicity appears at the exposure site, such as protein denaturation caused by caustic substances.
In contrast, systemic toxicity requires the toxic agent's absorption and distribution,...
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