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Updated: Jul 5, 2025

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抑制CYP1A1可以减轻素诱导的肝毒性

Ruoyue Huang1, Jingyi Duan1, Wen Huang2

  • 1Department of Gastroenterology & Hepatology, Laboratory of Metabolomics and Drug-Induced Liver Injury, State Key Laboratory of Biotherapy, and Frontiers Science Center for Disease-Related Molecular Network, West China Hospital, Sichuan University, Chengdu 610041, China.

Toxins
|January 22, 2024
PubMed
概括

过量服用胆固醇可以导致肝损伤. 抑制CYP1A1通过CASPASE-1-GSDMD途径减少氧化应激和热,从而减轻这种损伤,这表明CYP1A1是治疗点.

关键词:
在CYP1A1中.科尔奇辛 (Colchicine) 是一种可怕的药物.代谢 代谢 代谢 代谢氧化应激是一种氧化应激.热灭症是什么?

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