跨支气管干预在患有恶性中央气道阻塞的老年患者的可行性,耐受性和有效性:一项回顾性单一机构研究
Kosuke Kashiwabara1, Shinji Fujii, Shinsuke Tsumura
1Department of Respiratory Medicine, Kumamoto Regional Medical Center, Kumamoto, Japan.
American journal of clinical oncology
|January 22, 2024
概括
跨支气管干预 (TBIs) 是对患有恶性中央气道阻塞 (MCAO) 的老年患者的安全有效的息程序. 这项研究发现,接受TBI的老年和非老年患者之间的并发症率或结果没有显著差异.
科学领域:
- 肺部病理学 肺部病理学
- 干预性肺病学 干预性肺病学
- 在瘤学瘤学.
背景情况:
- 恶性中央气道阻塞 (MCAO) 在老年患者中带来了挑战.
- 由于年龄问题,医生经常犹在老年患者身上进行横支气管干预 (TBIs).
研究的目的:
- 评估TBI在老年人 (≥75岁) 与非老年人 (<75岁) 患有MCAO的患者的可行性,耐受性和有效性.
- 为了比较两个年龄组之间的并发症率和临床结果.
主要方法:
- 追溯性研究比较老年 (n=27) 和非老年 (n=50) 患有MCAO接受TBI的患者.
- 主要终点:TBI期间和之后的并发症发生率.
主要成果:
- 在老年人 (26%) 和非老年人 (30%) 组之间的并发症率没有显著差异 (P=0.706).
- 观察到成功的气道再通道化率 (93%与80%,P=0.197),症状改善率 (67%与76%,P=0.380) 和整体存活率 (6.1与7.3个月,P=0.704) 都相似.
结论:
- 跨支气管干预 (TBI) 是对患有恶性中枢气道阻塞 (MCAO) 的老年患者的一种安全有效的息选择.
- 年龄不应该成为对MCAO患者进行TBI的威.
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