在微生理系统中,SARS-CoV-2诱导的血管床的破坏是由支气管器官器官的I型干扰素引起的

Kazuya Fujimoto1, Yoshikazu Kameda1, Yuta Nagano1

  • 1Department of Micro Engineering, Kyoto University, Kyoto daigaku-Katsura, Nishikyo-ku, Kyoto 615-8540, Japan. yokokawa.ryuji.8c@kyoto-u.ac.jp.

Lab on a chip
|January 22, 2024
PubMed
概括

这项研究开发了一种微生理系统来模拟COVID-19血管效应. 它显示了支气管上皮感染,而不是直接的血管感染,通过细胞因子引起血管损伤,突出显示了干扰素反应的重要性.

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