优化抗逆转录病毒治疗,重点关注长期有效性和以人为中心的方法. 使用德尔菲流程的共识指导
Franco Maggiolo1, Sergio Lo Caputo2, Stefano Bonora3
1ASST Papa Giovanni XXIII, Bergamo, Italy.
The new microbiologica
|January 22, 2024
概括
专家们就监测艾滋病毒抗逆转录病毒治疗 (ART) 长期成功达成共识,强调减少毒性和生活质量. 本指南有助于个性化患者护理,以实现持续的病毒学和临床结果.
科学领域:
- 传染性疾病 传染性疾病
- 艾滋病毒 医学 艾滋病毒 医学
- 临床共识 临床共识
背景情况:
- 目前的抗逆转录病毒疗法 (ART) 策略的长期疗效数据仍然有限.
- 启动了一个共识过程,以建立管理和监测ART的最佳实践.
- 目前的ART管理需要更新患者持续健康的指导方针.
研究的目的:
- 制定关于定制和监测长期抗逆转录病毒疗法 (ART) 的共识声明.
- 确定艾滋病毒护理中患者监测和生活质量评估的首选方法.
- 为以人为中心的艾滋病毒治疗方法提供指导.
主要方法:
- 90名传染病专家组成的小组采用了德尔菲技术.
- 关于ART管理和患者随访的共识陈述被开发出来.
- 参与者代表了意大利的多个传染病中心.
主要成果:
- 在长期监测ART疗效的病毒学和免疫学参数上达成共识.
- 关于常规使用特定的炎症和免疫激活标志物,没有达成共识.
- 在优先考虑具有最小骨,脏和心血管毒性的ART方面达成一致.
- 在标准的艾滋病毒随访中,人们认识到对生活质量监测的有用性.
结论:
- 共识声明为执业人员提供了管理艾滋病毒感染者的指导.
- 建议以人为中心的方法来实现长期的病毒学和临床成功.
- 专注于尽量减少治疗毒性和监测生活质量对于持续的艾滋病毒治疗至关重要.
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