与对照组相比,TECH保护了MCI老年人的全球认知:一个随机对照试验
Noa Givon Schaham1, Zvi Buckman2, Debbie Rand3
1Department of Occupational Therapy, Faculty of Medicine, Steyer School of Health Professions, Tel Aviv University, Tel Aviv, Israel.
Aging clinical and experimental research
|January 22, 2024
概括
认知和健康增强药片 (TECH) 在轻度认知障碍 (MCI) 的老年人中改善了全球认知. 这种认知训练干预建议那些有进一步下降风险的人.
科学领域:
- 老年学是一门学科.
- 神经科学是一个神经科学.
- 认知心理学 认知心理学
背景情况:
- 通过平板电脑应用程序进行认知训练显示出对治疗轻度认知障碍 (MCI) 的希望.
- 患有MCI的老年人是保留认知功能的干预措施的目标人群.
研究的目的:
- 评估"增强认知和健康的平板电脑" (TECH) 计划的有效性.
- 为了确定TECH是否能改善或保持MCI诊断的老年人的认知能力.
主要方法:
- 一个单盲随机受控试验 (RCT) 涉及61名参与者 (65-89岁).
- 技术干预:每天使用平板电脑应用程序进行5周的自我训练,每周进行一次小组会议.
- 评估包括蒙特利尔认知评估 (MoCA),WebNeuro认知电池和生活质量的SF-12,以及前,后和6个月后续评估.
主要成果:
- 与标准护理组相比,TECH组在全球认知 (MoCA分数) 中的改善显著更高.
- 对于全球认知变化,观察到中间效应大小 (科恩d = 0.52-0.66).
- 40%的TECH参与者在MoCA分数中实现了临床重要差异的最小值,对照组为6.5%.
结论:
- 技术干预有效地鼓励日常自我训练,并保护MCI的老年人的全球认知功能.
- 建议TECH用于患有MCI的老年人,以减轻进一步认知恶化的风险.
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