用于脉冲波估计的重建性插值,以改善动脉的局部PWV测量
Ouyang Gu1, Bingbing He2, Li Xiong1
1Department of Electronic Engineering, Information School, Yunnan University, Kunming, 650091, Yunnan, China.
Medical & biological engineering & computing
|January 22, 2024
概括
这项研究引入了一种新方法,结合了运动跟踪和重建性插值,以提高脉冲波速度 (PWV) 测量的精度. 改进的技术减少了错误,从而使动脉刚性的评估更可靠.
科学领域:
- 生物医学工程 生物医学工程
- 医疗成像医学成像
- 心血管生理学心血管生理学
背景情况:
- 脉冲波速度 (PWV) 是动脉硬和心血管风险的关键指标.
- 准确测量局部PWV,特别是在常见动脉 (CCA),对于临床评估至关重要.
- 现有的基于超声波传输时间 (TT) 的PWV方法受到离散动脉壁运动 (AWM) 估计的限制.
研究的目的:
- 开发和验证一种新的方法,运动跟踪与重建性插值 (MTRI) 结合,以提高CCA中基于TT的本地PWV测量的准确性.
- 为了减少来自超声波无线电频率 (RF) 信号的AWM和PWV估计量的量化错误.
主要方法:
- 开发了MTRI方法,将运动跟踪与超声波射频信号的正常化交叉相关函数 (NCCFs) 的重构插值结合在一起.
- 使用MTRI方法计算了AWMs和本地PWV,并使用超声波模拟与传统方法比较结果.
- 在30名健康受试者中使用布兰德-阿尔特曼分析和变化系数验证了该方法的性能.
主要成果:
- 在模拟中,MTRI方法显著降低了AWM (从1.14%到0.60%) 和本地PWV (从7.48%到4.61%) 的正常化根平均平方误差 (NRMSEs).
- 超声波模拟显示,不同年龄组的精度有所提高.
- 在健康人群中的验证证实了该方法在动脉局部PWV测量方面提高了准确性和可重复性.
结论:
- 用于脉冲波估计的重构插值有效地提高了动脉局部PWV测量的准确性和可重复性.
- 该MTRI方法提供了一个更精确的方法,通过PWV评估动脉硬度.
- 这一进步为更可靠的非侵入性心血管风险评估提供了潜力.
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