提供者对在医院获得的肺炎的抗生素启动策略的认识
Aubrey C Swilling1, Jacob C O'Dell1, Robel T Beyene2
1Department of Surgery, University of Kansas Medical Center, Kansas City, Kansas, USA.
疑似肺炎的快速抗生素启动是常见的. 然而,提供者报告了更大的舒适度和感知更高的坚持立即开始抗生素与等待样本结果在通风患者相比.
科学领域:
- 临界护理医学 临界护理医学
- 传染性疾病 传染性疾病
- 临床实践指南 临床实践指南
背景情况:
- 对于疑似感染,迅速开始使用抗生素是一种广泛的做法,尽管最近有批评.
- 不同的抗生素启动策略的提供者舒适度水平仍未得到充分研究.
- 这项研究解决了了解提供者对肺炎抗生素时间的看法方面的差距.
研究的目的:
- 调查立即抗生素启动和样本启动抗生素协议之间的提供者舒适度和坚持感知的差异.
- 评估提供者对延迟抗生素的舒适性,直到有客观的感染证据.
主要方法:
- 对参加多中心试验的重症监护重症监护医生进行的前性调查,该试验涉嫌肺炎的抗生素限制 (TARPP).
- 在TARPP试验中,在疑似肺炎的通风患者中,立即启动抗生素与样本启动的抗生素启动进行比较.
- 医生被调查舒适度和每个治疗臂的感知依从度.
主要成果:
- 从31位独特的参与者那里收集了51个调查答案.
- 与样本启动组相比,提供者认为立即开始抗生素的坚持率明显高 (37.5%始终坚持) (11.1%始终坚持;p=0.045).
- 提供者报告说,等待客观感染证据的舒适度显著下降 (83.3%非常满意立即启动,而40.7%非常满意样本启动;p=0.004).
结论:
- 供应商的舒适度和坚持感知可能在空气呼吸患者疑似肺炎的立即和样本启动的抗生素策略之间存在差异.
- 研究结果表明,提供者的舒适性是影响遵守抗生素启动协议的一个因素.
- 这些见解对于设计未来的临床试验和优化抗生素管理计划至关重要.
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