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Updated: Jul 5, 2025

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对大肠直肠癌公共蛋白质组数据集的综合元分析,用于生物标志物发现和验证

Javier Robles1,2, Ananth Prakash3, Juan Antonio Vizcaíno3

  • 1Department of Molecular Biomedicine, Centro de Investigaciones Biológicas Margarita Salas, Consejo Superior de Investigaciones Científicas, Madrid, Spain.

PLoS computational biology
|January 22, 2024
PubMed
概括

研究人员重新分析了公共蛋白质组学数据,以找到新的结直肠癌 (CRC) 生物标志物. 他们确定了五种可检测到血液中的蛋白质,这些蛋白质可以帮助分类患者并预测预后,证明了重用现有数据的价值.

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相关概念视频

Proteomics01:33

Proteomics

A proteome is the entire set of proteins that a cell type produces. We can study proteomes using the knowledge of genomes because genes code for mRNAs, and the mRNAs encode proteins. Although mRNA analysis is a step in the right direction, not all mRNAs are translated into proteins.
Proteomics is the study of proteomes' function. It involves the large-scale systematic study of the proteome to denote the protein complement expressed by a genome. Scientist Mark Wilkins coined the term...
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