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Updated: Jul 5, 2025

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Brg1/PRMT5核复合体在IPF介质细胞前代细胞中表观遗传调节FOXO1

Aiham H Jbeli1, Libang Yang1, Hong Xia1

  • 1Department of Medicine, University of Minnesota, Minneapolis, Minnesota, United States.

American journal of physiology. Lung cellular and molecular physiology
|January 22, 2024
PubMed
概括

研究人员在异常性肺纤维化 (IPF) 肺中发现了纤维化介质原生细胞 (MPC). 一个Brg1/PRMT5复合体表观遗传调节FOXO1,促进IPF MPC的自我更新和驱动疾病的进展.

关键词:
在IPF中,IPF是IPF.氨酸甲基转移酶是氨酸甲基转移酶.染色体改造器 染色体改造器表观遗传调节 表观遗传调节介质细胞的前代细胞.

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