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Updated: Jul 5, 2025

Deacetylation Assays to Unravel the Interplay between Sirtuins SIRT2 and Specific Protein-substrates
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特定的线粒体脱酶抑制剂 Sirtuin 4 具有细胞活动

Martin Pannek1, Zayan Alhalabi2, Daniela Tomaselli3

  • 1Department of Biochemistry, University of Bayreuth, 95440 Bayreuth, Germany.

Journal of medicinal chemistry
|January 22, 2024
PubMed
概括

研究人员鉴定出了与衰老和疾病相关的线粒体蛋白 Sirtuin 4 (Sirt4) 的强有力的小分子抑制剂. 这些一流的化合物为研究Sirt4和开发潜在治疗方法提供了新的工具.

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