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Updated: Jul 5, 2025

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一种新型核因子的抗炎作用 - - 基基的抑制性衍生物[3,4-d]Pyrimidine在三个炎症模型中

Hiroyuki Baba1, Tadashi Hosoya2, Ryosuke Ishida1

  • 1Department of Rheumatology, Graduate School of Medical and Dental Sciences (H.B., T.H., S.Y.), Institute of Biomaterials and Bioengineering (R.I., S.H., H.Ka.), and School of Medicine, Graduate School of Medical and Dental Sciences (Y.K.), Tokyo Medical and Dental University, Tokyo, Japan; and Graduate School of Pharmaceutical Sciences, University of Tokyo, Tokyo, Japan (K.T., H.Ku.).

The Journal of pharmacology and experimental therapeutics
|January 22, 2024
PubMed
概括

一种新型化合物INH #1通过抑制核因子-κB (NF-κB) 在急性肝炎和关节炎动物模型中有效降低了炎症. 这表明INH#1作为潜在的炎症性疾病的新疗法.

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