怀孕早期的全静电负荷和睡眠呼吸障碍
Amir J Lueth1, Amanda A Allshouse1, Robert M Silver1
1Department of Obstetrics and Gynecology, University of Utah Health, Salt Lake City, UT, USA.
概括
怀孕早期高静态负荷与孕妇睡眠呼吸障碍 (SDB) 有显著的关联. 即使调整了诸如体重指数等因素后,这种关联仍然存在,突出强调了压力.
科学领域:
- 生殖健康 生殖健康
- 睡眠医学 睡眠医学
- 心血管健康 心血管健康
背景情况:
- 睡眠呼吸障碍 (SDB) 是怀孕期间普遍存在的疾病,与孕妇和胎儿的不良后果有关.
- 静态负荷,慢性压力的度量,已与各种健康状况有关,但其在妊娠并发症 (如SDB) 中的作用不太清楚.
研究的目的:
- 调查怀孕早期高静态负荷与怀孕期间睡眠呼吸障碍 (SDB) 存在的关联.
主要方法:
- 这项研究基于12个生物标志物在第一季度定义了高静态负荷.
- 在怀孕早期和中期使用Embletta-Gold设备客观测量睡眠呼吸障碍 (SDB).
- 使用多变量后勤回归模型来评估关联,并对潜在的混因素进行调整.
主要成果:
- 高静态负荷存在于队列的35.0%,SDB发生在8.3%的怀孕中.
- 在高全静电负荷和SDB之间发现了显著的关联 (aOR=5.3),以及在怀孕早期 (aOR=7.0) 和怀孕中期 (aOR=5.8) 的SDB.
- 全静电负荷和SDB之间的关联没有受到肥胖的显著改变,即使在将体重指数排除在全静电负荷得分之外,它仍然是显著的.
结论:
- 怀孕早期的高静态负荷是怀孕期间SDB的重要独立预测因素.
- 这些发现表明慢性压力和SDB之间存在复杂的相互作用,需要进一步调查潜在的双向关系.
- 了解这种关联可能为孕妇群体的SDB预防和管理提供新的途径.
相关概念视频
01:21Sleep Apnea
157
Sleep apnea is a condition where breathing stops intermittently during sleep, often leading to significant health issues. Each episode can last from 10 to 20 seconds or more and is frequently accompanied by a brief arousal from sleep. This disturbance, largely unnoticed by the individual, can lead to severe daytime fatigue. Commonly, individuals seek help after being informed by their partners about loud snoring and noticeable breathing pauses during sleep.
The condition is more prevalent among...
The condition is more prevalent among...
157
01:07Teratogenicity
2.5K
The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
2.5K
01:17Sleepwalking and Sleep Talking
166
Somnambulism, commonly known as sleepwalking, involves individuals engaging in activities ranging from simple walking to more complex behaviors such as driving. Sleepwalking typically occurs during the slow-wave sleep stages 3 and 4 early in the night when the person is not dreaming, contradicting the myth that sleepwalkers are acting out their dreams.
Factors that increase the likelihood of sleepwalking include sleep deprivation and alcohol consumption. Contrary to common beliefs, it is safe...
Factors that increase the likelihood of sleepwalking include sleep deprivation and alcohol consumption. Contrary to common beliefs, it is safe...
166
01:13Insufficient Sleep and Sleep Deprivation
145
Insufficient sleep refers to not getting the recommended amount of sleep for optimal functioning, even if it's just slightly less than needed. Sleep insufficiency may occur due to lifestyle choices, such as staying up late for social events or work, resulting in routinely getting less sleep than required. For example, consistently sleeping 6 hours when the body needs 7-9 hours can lead to cumulative effects on health and well-being.
Sleep deprivation is a more severe form of sleep loss...
Sleep deprivation is a more severe form of sleep loss...
145
01:30Respiratory System Abnormal Finding I: Inspection and Percussion
273
Respiratory system abnormalities are a significant concern in healthcare due to their potential to indicate underlying severe conditions like Chronic Obstructive Pulmonary Disease (COPD), asthma, and pneumonia. These abnormalities can often be detected through physical examination methods like inspection and percussion.
Inspection Findings
During an inspection, several findings may suggest the presence of respiratory distress or disease. Pursed-lip breathing, where exhalation is slowed by...
Inspection Findings
During an inspection, several findings may suggest the presence of respiratory distress or disease. Pursed-lip breathing, where exhalation is slowed by...
273