在先天盲人中,声音抑制了视力恢复后最早的视觉皮层处理
Suddha Sourav1, Ramesh Kekunnaya2, Davide Bottari3,4
1Biological Psychology and Neuropsychology, University of Hamburg, Hamburg, Germany. suddha.sourav@uni-hamburg.de.
Communications biology
|January 22, 2024
概括
即使在恢复视力后,出生盲人的视觉皮层在声音与视觉刺激同时发生时显示抑制的活动. 这表明大脑中持续存在的交叉模式可塑性.
科学领域:
- 神经科学是一个神经科学.
- 神经生物学 神经生物学 神经生物学
- 视觉神经科学是一种神经科学.
背景情况:
- 先天性失明导致交叉可塑性,视觉皮层表现出非视觉活动.
- 目前尚不清楚这种跨模式激活是否会在视力恢复后继续存在.
研究的目的:
- 为了调查早期视觉皮层处理阶段的交叉调制是否在先天性模式视觉失明后恢复视力的人群中持续存在.
主要方法:
- 在患有先天模式视觉失明的个体中利用视觉事件相关潜力 (VERP),这些人恢复了视力.
- 对视觉刺激的反应进行了比较,与有视觉控制对象和晚期出现视觉障碍的个体相比,有或没有同时出现的声音.
主要成果:
- 视力恢复的个体出生模式视力失明显示,当声音伴随着视觉刺激时,抑制了早期视网膜皮质视觉活动 (<100毫秒).
- 这种抑制是空间特定的,在典型的视力控制和以后出现视力障碍的个体中不存在.
结论:
- 提供了从先天性视觉丧失中恢复后视觉皮层中持久的交叉模式活动的证据.
- 推测在敏感的发育期内,多余的交叉模态乳头输入可能是这种持续调节的基础.
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