实施CAR-T活动和管理CAR-T患者的成本:一项探索性研究
Maria Caterina Cavallo1, Marianna Cavazza1, Francesca Bonifazi2
1Cergas, Centre for Research on Health and Social Care Management, SDA Bocconi School of Management, Bocconi University, Via Sarfatti, 10, Milano, 20136, Italy.
BMC health services research
|January 23, 2024
概括
实施化学抗原受体T细胞 (CAR-T) 治疗需要付出大量成本,质量保证是主要的驱动因素. 医疗保健支付人应考虑为CAR-T临床途径提供捆绑支付,以有效管理费用.
科学领域:
- 在瘤学瘤学.
- 卫生经济学 卫生经济学
- 细胞疗法细胞疗法
背景情况:
- 化学抗原受体T细胞 (CAR-T) 疗法提供了创新,但由于高成本和组织影响,对医疗保健支付人提出了挑战.
- 现有的文献侧重于CAR-T评估和市场准入,对实施和全临床途径成本的数据有限.
研究的目的:
- 评估与实施CAR-T疗法相关的成本.
- 确定管理CAR-T临床途径的全部成本.
主要方法:
- 使用了基于活动的成本计算 (ABC) 方法.
- 分析是在两个授权的意大利CAR-T中心进行的,至少有20名患者接受治疗.
主要成果:
- 一个中心的CAR-T实施成本估计为131万欧元,其中77%归因于质量保证.
- 患者的平均费用在进入途径时为48,000欧元-57,000欧元,在随访时为96,000欧元-106,000欧元.
- 住院和输液费用占成本的70%以上,往往超过实际住院费用.
结论:
- 卡特疗法具有重大组织和经济影响,需要投资实施.
- 服务费/节目不涵盖的活动需要评估.
- 建议在CAR-T临床途径中转向捆绑支付.
更多相关视频
相关概念视频
Modeling in Therapy
84
Modeling, a key technique in therapy, uses observational learning to help clients acquire and practice new skills by watching therapists demonstrate desired behaviors. This approach, rooted in Albert Bandura's concept of vicarious learning, plays a significant role in therapeutic interventions for various psychological conditions, including social anxiety, ADHD, and depression.
Participant Modeling
Participant modeling involves therapists demonstrating calm and effective behaviors in...
Participant Modeling
Participant modeling involves therapists demonstrating calm and effective behaviors in...
84
Group Therapy
35
Group therapy is a sociocultural approach to psychological treatment, where individuals with shared psychological challenges come together under the guidance of a mental health professional. This therapeutic modality offers unique opportunities for individuals to connect, share, and grow within the context of a supportive group. By fostering mutual understanding and collaboration, group therapy can address a range of psychological concerns effectively, often complementing or surpassing the...
35
Methods of Documentation VI: Case Management Model
574
The case management model is a multidisciplinary approach that involves healthcare professionals from diverse disciplines, such as physicians, nurses, therapists, social workers, and pharmacists, working collaboratively to address the various needs of patients. Each healthcare professional brings unique expertise and perspectives, contributing to a more comprehensive understanding of the patient's condition and tailoring treatment plans accordingly.
For example, a patient with a chronic...
For example, a patient with a chronic...
574
Couples Therapy
44
Couples therapy is a therapeutic approach designed to help individuals in intimate relationships address conflicts, improve communication, and foster healthier dynamics. It is appropriate for couples at various stages, including those who are dating, married, or in long-term partnerships, and aims to support partners in navigating their unique relational challenges.
Core Principles and Techniques
Couples therapy often incorporates cognitive-behavioral principles to identify and modify negative...
Core Principles and Techniques
Couples therapy often incorporates cognitive-behavioral principles to identify and modify negative...
44
Psychotherapy
106
Psychotherapy is a versatile, nonmedical approach aimed at helping individuals address emotional, behavioral, and interpersonal issues to enhance their overall well-being. It can involve one-on-one sessions, couples counseling, or small group discussions with a therapist. The therapeutic process includes various techniques such as open discussion, interpretation of thoughts and behaviors, active listening, positive reinforcement, and role modeling. Psychotherapy aims to support individuals in...
106
Operant Conditioning Intervention
58
Operant conditioning serves as a foundational principle in therapeutic interventions aimed at modifying maladaptive behaviors. Central to this approach is the notion that behaviors, both adaptive and maladaptive, are learned through reinforcement. By analyzing the environmental factors that reinforce problematic behaviors, clinicians can design interventions to weaken these reinforcements and replace maladaptive behaviors with healthier alternatives.
In operant conditioning, behaviors that are...
In operant conditioning, behaviors that are...
58


