在大视网膜内激光和手术后的凯托洛拉克眼滴后的神经损伤性角质病变:一系列病例
Giovanni Fossati1,2, Elena Bartoli2, Alessio Montericcio2
1Department of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, Pieve Emanuele, 20072 Milan, Italy.
European journal of ophthalmology
|January 23, 2024
概括
手术后的Ketorolac眼滴可能会增加视网膜脱落手术后神经营养性角质病变 (NK) 的风险. 停止使用这些NSAID滴剂并使用辅助疗法在这些患者中成功治疗了NK.
科学领域:
- 眼科医生 眼科 眼科
- 视网膜外科手术 视网膜外科手术
- 角膜疾病 角膜疾病
背景情况:
- 神经缩性角膜病变 (NK) 是一种严重的眼睛疾病,影响角膜健康.
- 带有视网膜内激光器的Pars plana vitrectomy (PPV) 是一种常见的风湿性视网膜脱落 (RRD) 的程序.
- 手术后的非类固醇抗炎药物 (NSAIDs) 经常使用,但可能会产生眼部副作用.
研究的目的:
- 调查Ketorolac Tromethamine眼滴与神经缩性角质病变 (NK) 的发展之间的潜在联系.
- 报告一系列经过帕斯普拉纳视切除术 (PPV) 和视网膜内激光手术后出现NK的病例.
- 评估停止使用NSAID滴剂在治疗术后NK的疗效.
主要方法:
- 一个由五名患者组成的病例系列,这些患者在PPV和RRD的endolaser后发展了NK.
- 患者在术后接受了凯托洛拉克甲胺0.5%眼滴.
- 对NK的治疗包括停止Ketorolac,治疗性隐形眼镜,胎膜贴片和滑剂.
主要成果:
- 五名患者在PPV和内激光手术后出现了神经缩性角质病变 (NK).
- 所有患者都接受了手术后的Ketorolac Tromethamine 0.5%眼滴.
- 通过停止服用Ketorolac并采用辅助疗法,可以成功治疗NK.
结论:
- 手术后的Ketorolac眼滴可能会降低角膜敏感性,增加皮质干扰和内激光器PPV后NK的风险.
- 需要进一步的研究,以了解NSAIDs对接受PPV和广泛的内激光手术的患者角膜敏感性的影响.
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