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基于转录组分析的基因查与北京的脂肪沉积相关的基因

Bozhi Shi¹, Ziyue Zhang¹, Xueze Lv²

¹College of Veterinary Medicine, China Agricultural University, Beijing 100193, China.

Animals : an open access journal from MDPI

|January 23, 2024

概括

南口1 北京与京北京相比,皮下脂肪沉积率高. 转录组分析确定了调节子脂肪代谢和沉积的关键基因.

科学领域:

动物科学动物科学
基因组学就是基因组学.
生物化学生物化学

背景情况:

皮下脂肪沉积对于评估肉至关重要,影响肉质和料效率.
了解皮下脂肪沉积的遗传机制对于改善子品种至关重要.

研究的目的:

为了研究南口1和京甸佩金之间的皮下脂肪中的差异表达基因 (DEGs).
确定参与调节皮下脂肪沉积的候选基因和分子通路.

主要方法:

屠宰性能分析和全转录组测序对144只42天大龄的北京 (南科1和京甸品种) 进行.
进行了差异基因表达分析和基因和基因组京都百科全书 (KEGG) 路径丰富分析.

主要成果:

南口一的乳腺肌肉,腹部脂肪和皮下脂肪产量明显高于京东.
数以千计的DEG被确定,在与脂解,胆酸生物合成和不和脂肪酸生物合成相关的途径中得到丰富.
包括SCD,FGF7,LTBP1,PNPLA3,ADCY2和ACOT8在内的候选基因参与调节皮下脂肪沉积.

结论:

南口1 北京与京北京相比,具有更高的脂肪沉积能力.
已确定的候选基因通过调节脂肪合成和分解途径来调节子脂肪沉积.

关键词:

北京子是什么意思?在RNA-seqqq.脂肪代谢脂肪的代谢屠宰表现屠宰表现屠宰表现皮下脂肪是一种皮下脂肪.

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